Job Description

Sr. Diretor/Executive Director, Supply Chain

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About Jade Biosciences

Jade Biosciences is focused on developing innovative, best-in-class therapies to address critical unmet needs in autoimmune diseases. Our lead candidate, JADE101, is designed to inhibit the cytokine APRIL (A Proliferation-Inducing Ligand) and is being developed for the treatment of immunoglobulin A nephropathy (IgAN), a chronic kidney disease that can impair kidney function over time. JADE101 aims to reduce harmful IgA antibodies, lower proteinuria (a key marker of kidney damage), and preserve long-term kidney function. A Phase 1 healthy-volunteer study of JADE101 is ongoing, with interim, biomarker-rich data expected in the first half of 2026. Jades pipeline also includes a second development candidate, JADE201, and an undisclosed antibody discovery program, JADE-003, both currently in preclinical development. For more information, visit JadeBiosciences.com and follow us on LinkedIn.

Role Overview

We are seeking a strategic, highly skilled and motivated Sr/Executive Director of Supply Chain, to join our dynamic team. The Director of Supply Chain will lead the drug product clinical supply chain strategy, planning and execution for early and late-stage biologics clinical programs within the CMC group. The successful candidate will be a self-starter with demonstrated ability to develop clinical supply chain strategy using CDMOs and manage reliable clinical supply across complex global clinical studies. The successful candidate will be responsible for building the supply chain function from the ground-up, building and mentoring a team of supply chain professionals, to support Jades exciting pipeline. In this high impact role, the candidate will have the opportunity to make a significant contribution towards the development of potentially transformational, disease-modifying therapies targeting autoimmune diseases.

Key Responsibilities

• Lead the Clinical Supply Function: Provide strategic and operational leadership for the clinical supply organization at Jade. Build and scale the Clinical Supply Chain function through a combination of internal headcount and external partnerships to meet evolving business and program needs.
• Define Clinical Supply Strategy: Develop and implement the overall clinical supply strategy for all Jade programs, ensuring the timely, compliant, and cost-effective delivery of clinical materials across all phases of development.
• Develop Integrated Global Supply Plans: Establish and manage comprehensive global supply chain plans spanning early-stage (Phase 1/2) through late-stage (Phase 3) development, with a forward-looking approach toward commercial readiness.
• Collaborate Cross-Functionally: Partner closely with Clinical Development, Clinical Operations, and CMC teams to forecast, align, and continuously update clinical supply requirements for ongoing and future studies.
• Oversee Clinical Supply Operations: Direct all aspects of labeling, packaging, cold-chain storage, and distribution for various drug product formats, including drug-in-vial, pre-filled syringe, and autoinjector, in alignment with individual program specifications.
• Manage External Partnerships: Build, maintain, and optimize strategic relationships with contract development and manufacturing organizations (CDMOs) and critical suppliers to ensure operational excellence, quality, and reliability of supply.
• Ensure Compliance and Quality: Maintain full compliance with cGMP, ICH guidelines, and all applicable local and global regulatory requirements governing supply chain activities, ensuring Jades continued commitment to quality and patient safety.

Qualifications

• Senior Director: Bachelors or Masters degree (or equivalent) in Life Sciences, Chemical Engineering, or a related field, with 12+ years of progressive experience in biologics drug product supply chain management.
• Executive Director: Bachelors or Masters degree (or equivalent) in Life Sciences, Chemical Engineering, or a related field, with 15+ years of progressive experience in biologics drug product supply chain management.
• Proven expertise in managing clinical supply chain for drug-in-vial and combination products, including pre-filled syringes and autoinjectors, within cold chain environments.
• Experience supporting both early-stage and late-stage clinical development programs, with a strong understanding of global supply and distribution requirements.
• Demonstrated success in building and scaling supply chain functions, and in supporting multi-country global Phase 3 studies for biologic combination products.
• Prior experience overseeing late-stage drug product development and ensuring seamless collaboration across manufacturing, quality, and clinical operations.
• Comprehensive understanding of global regulatory and import/export requirements, including region-specific guidelines across Europe, North America, and Rest of World (ROW).
• Exceptional communication, leadership, and interpersonal skills, with the ability to influence and collaborate effectively across internal teams and external partners.
• A strategic, data-driven leader with strong problem-solving capabilities and a demonstrated ability to navigate complex, fast-paced environments.

Position Location

This is a remote role; periodic travel to team and company events is required.

The anticipated salary range for candidates for this role at the Sr Director level is $255,000 $280,000 and at the Executive Director level is $280-$300,000. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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